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503615-03-0

  • Product Name:3-Morpholino-1-(4-nitrophenyl)-5 6-dihydropyridin-2(1H)-one
  • Molecular Formula:C15H17N3O4
  • Molecular Weight:303.318
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Product Details

Purity:99%

High Purity Factory Supply 3-Morpholino-1-(4-nitrophenyl)-5 6-dihydropyridin-2(1H)-one 503615-03-0

  • Molecular Formula:C15H17N3O4
  • Molecular Weight:303.318
  • Boiling Point:506.532 °C at 760 mmHg 
  • PKA:3.11±0.20(Predicted) 
  • Flash Point:260.141 °C 
  • PSA:78.60000 
  • Density:1.357 g/cm3 
  • LogP:2.07370 

503615-03-0 Relevant articles

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503615-03-0 Process route

morpholine
110-91-8,99108-56-2

morpholine

3,3-dichloro-1-(4-nitrophenyl)piperidine-2-one
881386-01-2

3,3-dichloro-1-(4-nitrophenyl)piperidine-2-one

3-(morpholin-4-yl)-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
503615-03-0

3-(morpholin-4-yl)-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

Conditions
Conditions Yield
at 120 ℃; for 2h; Inert atmosphere;
90.4%
at 130 ℃; for 1.5h;
87.6%
at 130 ℃; for 5h;
64.5%
3,3-dichloro-1-(4-nitrophenyl)piperidine-2-one; With hydrogenchloride; In water; at -5 - 30 ℃; for 2h; Inert atmosphere;
morpholine; In water; at 110 ℃; for 2h; Inert atmosphere;
62%
at 130 ℃; for 1.5h;
In N,N-dimethyl-formamide; for 1h; Reflux;
85.73 g
morpholine
110-91-8,99108-56-2

morpholine

1-(4-nitrophenyl)piperidine-2-one
38560-30-4

1-(4-nitrophenyl)piperidine-2-one

3-(morpholin-4-yl)-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one
503615-03-0

3-(morpholin-4-yl)-1-(4-nitrophenyl)-5,6-dihydropyridin-2(1H)-one

Conditions
Conditions Yield
1-(4-nitrophenyl)piperidine-2-one; With phosphorus pentachloride; Cooling with ice;
morpholine; for 2h; Reflux;
66%
1-(4-nitrophenyl)piperidine-2-one; With phosphorus pentachloride; In chloroform; for 2h; Heating;
morpholine; at 130 ℃; for 1h; Further stages.;
65.2%
1-(4-nitrophenyl)piperidine-2-one; With phosphorus pentachloride; In chloroform; at 20 ℃;
morpholine; for 2h; Heating / reflux;
53%
1-(4-nitrophenyl)piperidine-2-one; With phosphorus pentachloride; In chloroform; for 3.5h; Heating / reflux;
morpholine; Heating / reflux;
1-(4-nitrophenyl)piperidine-2-one; With phosphorus pentachloride; In dichloromethane; at 0 - 30 ℃; for 2.5h;
morpholine; at 125 - 130 ℃; for 1h;
16 g
1-(4-nitrophenyl)piperidine-2-one; With phosphorus pentachloride; In dichloromethane; at 0 - 30 ℃; for 2.5h;
morpholine; at 125 - 130 ℃; for 1h;
16 g

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