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pd_meltingpoint:209-211 °C(lit.)
Appearance:white crystalline powder
Purity:99%
Quality products make an important contribution to long-term revenue and profitability. We provide high quality 2'-Deoxycytidine monohydrate (CAS 951-77-9), at a very affordable prices to our customers.
2'-Deoxycytidine is a deoxyribonucleotide that is used in the synthesis of DNA. It stimulates the expression of cardiac-specific genes and proteins, and directs mesenchymal stem cells towards cardiomyogenic differentiation.
{5'-d(ATGGGC[15N3,13C1-2'-G]GCATGAAC)-3'}*{3'-d(TACCCGCCGTACAAG)-5'}
![2,2-diamino-4-[(2-deoxy-β-D-erythro-pentofuranosyl)amino]-2,5-dihydrooxazol-5-one](/upload/2023/5\a86ce7ee-861c-4f54-90b9-7d583d15eb06.png)
2,2-diamino-4-[(2-deoxy-β-D-erythro-pentofuranosyl)amino]-2,5-dihydrooxazol-5-one
7,8-dihydro-8-oxo-2'-deoxyguanosine
2'-deoxyadenosine
2'-Deoxycytidine
thymidine
| Conditions | Yield |
|---|---|
|
{5'-d(ATGGGC[15N3,13C1-2'-G]GCATGAAC)-3'}*{3'-d(TACCCGCCGTACAAG)-5'}; With oxygen; sodium chloride; riboflavin; In aq. buffer; for 0.333333h; pH=7; Irradiation;
With nuclease P1; deferoxamine; ammonium acetate; zinc(II) chloride; alkaline phosphatase; In aq. buffer; at 37 ℃; for 2h; pH=5.3; Reagent/catalyst; Enzymatic reaction;
|
{5'-d(ATGGG(5-methyl-C)[15N3,13C1-2'-G]GCATGAAC)-3'}*{3'-d(TACCCGCCGTACAAG)-5'}
2,2-diamino-4-[(2-deoxy-β-D-erythro-pentofuranosyl)amino]-2,5-dihydrooxazol-5-one
7,8-dihydro-8-oxo-2'-deoxyguanosine
2'-deoxyadenosine
2'-Deoxycytidine
thymidine
| Conditions | Yield |
|---|---|
|
{5'-d(ATGGG(5-methyl-C)[15N3,13C1-2'-G]GCATGAAC)-3'}*{3'-d(TACCCGCCGTACAAG)-5'}; With oxygen; sodium chloride; riboflavin; In aq. buffer; for 0.333333h; pH=7; Irradiation;
With nuclease P1; deferoxamine; ammonium acetate; zinc(II) chloride; alkaline phosphatase; In aq. buffer; at 37 ℃; for 2h; pH=5.3; Reagent/catalyst; Enzymatic reaction;
|
The CAS number of 2'-Deoxycytidine monohydrate is 951-77-9.
More information of 2'-Deoxycytidine monohydrate 951-77-9 are:
|
CAS Number |
951-77-9 |
|
Density |
1.733 g/cm3 |
|
Melting Point |
209-211 °C(lit.) |
|
Boiling Point |
497.625 °C at 760 mmHg |
|
Flash Point |
254.754 °C |
|
Refractive Index |
59 ° (C=1, H2O) |
|
HS CODE |
PRICE |
|
PSA |
119.83000 |
|
LogP |
-1.01690 |
|
Pka |
14.03±0.60(Predicted) |
Synonyms for 2'-Deoxycytidine monohydrate 951-77-9:Cytidine,deoxy- (6CI,7CI);1-(2-Deoxy-b-D-ribofuranosyl)cytosine;2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-b-D-erythro-pentofuranosyl)-;2'-Deoxycytidine;4-Amino-1-(2-deoxy-b-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone;Cytosine deoxyribonucleoside;Cytosine deoxyriboside;Deoxycytidine;Deoxyribose cytidine;
The chemical formula of 2'-Deoxycytidine monohydrate is C9H13N3O4 which containing 9 Carbon atoms,13 Hydrogen atoms,3 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of 2'-Deoxycytidine monohydrate is 227.22.
2′-deoxycytidine (2-DC) belongs to the cytidine family. 2'-Deoxycytidine has been shown to inhibit the kinase activity of IL-2 receptor and Toll-like receptor, which are proteins that regulate the immune response. 2'-Deoxycytidine also inhibits DNA polymerase activity and thermal expansion, which may make it a good candidate as an anticancer drug. 2'-deoxycytidine (2-DC) forms covalent adducts with DNA and irreversibly inhibits methyltransferase.
Relevant articles related to 2'-Deoxycytidine monohydrate:
|
Article |
Source |
| The α-D-anomer of 2′-deoxycytidine: crystal structure, nucleoside conformation and Hirshfeld surface analysis |
S. Budow-Busse, Y. Chai, S. L. Müller, C. Daniliuc and F. Seela Acta Cryst. (2021). C77, 202-208 |
|
Identification of Flavin Mononucleotide as a Cell-Active Artificial N6-Methyladenosine RNA Demethylase |
Xie, Li-Jun,Yang, Xiao-Ti,Wang, Rui-Li,Cheng, Hou-Ping,Li, Zhi-Yan,Liu, Li,Mao, Lanqun,Wang, Ming,Cheng, Liang supporting information, p. 5028 - 5032 (2019/03/17) |
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